Hi
We cruise for up to 6 weeks with our 3 indoor guineapigs on board. It is possible but you need to plan.
As mentioned above, temperature control is important. It can get very hot on board in the summer even with the doors and windows open and we've had a couple of instances of heat exhaustion. Fans pointing directly at the cage are not recommended so it is cooled bottles of water wrapped in towels and seeking shade.
Conversely, too cold is a problem. Their hutch is on the floor below the waterline so we have a Celotex pad, slightly smaller than the hutch underneath. We have a padded curtain to insulate the hutch at night and if particularly cold we lift them onto the table, bearing in mind that the draught from the door vents can cause a problem when they're on the floor.
If very cold or very hot, my partner gets up in the night to check they are OK!
You need space to store the hay although if you have access to a car (which I think you might as a working CC), that may not be so much of a problem. Similarly, access to fresh veg is difficult sometimes when in the middle of nowhere.
Finally, it can be dusty on board and that can cause respiratory problems. Ours run freely on the carpet so a bit more insulation but won't venture onto the wood surfaces.
Hope this helps.
On behalf of Daphne, Mimi and Florence.